Ding, J.L., Navas, M.A., Ho, B.. Molecular Marine Biology and Biotechnology, 1995
Why Is This Living Fossil's Blood So Expensive?
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Before any vaccine, any IV drug, or any injectable medicine reaches your body, it has to pass through the blood of this animal first. Blood that is — literally — electric blue.
Where this comes from
10 sources
9 claims
Every claim below links to the sources behind it. Peer-reviewed research and public records come first.
What the film says
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LAL made from horseshoe crab blood has been reported to cost about $60,000 a gallon.
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Horseshoe crabs are not crustaceans; they are more closely related to arachnids such as spiders and scorpions.
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Blood is drawn from the pericardium and the crabs are then returned to the water.
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Delaware Bay is the main spawning area and the largest shorebird staging area on the Atlantic Flyway.
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A female may spawn over several nights to lay 100,000 or more eggs.
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Rufa red knots fly more than 9,300 miles each spring from as far as Tierra del Fuego to the Canadian Arctic.
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In Delaware Bay red knots feed almost exclusively on horseshoe crab eggs.
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Overharvest of horseshoe crabs in the 1990s was the key factor in red knot declines; numbers fell about 75% in some key areas since the 1980s.
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Jeak Ling Ding's lab at the National University of Singapore cloned horseshoe crab factor C in 1995 and built recombinant factor C proteins by 2000.
Sources
Peer-reviewed
Tan, N.S., Ho, B., Ding, J.L.. FASEB Journal, 2000
Krisfalusi-Gannon, Jordan; Ali, Waleed; Dellinger, Kristen; et al.. Frontiers in Marine Science, 2018
Agencies and public records
U.S. Fish & Wildlife Service
Atlantic States Marine Fisheries Commission
U.S. Fish & Wildlife Service
U.S. Fish & Wildlife Service, 2014
+ 1 more from USFWS
U.S. Fish & Wildlife Service, 2022
Reporting
Business Insider, 2018
Source of the widely repeated $60,000-a-gallon figure, which is a press value, not a published market price.
Palaeontology Online
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